anti-METTL11A antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Rabbit Polyclonal antibody recognizes METTL11A |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | METTL11A |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human METTL11A |
| 偶联标记 | Un-conjugated |
| Protein Full name | N-terminal Xaa-Pro-Lys N-methyltransferase 1 |
| 別名 | NTMT1; N-Terminal Xaa-Pro-Lys N-Methyltransferase 1; NRMT1; NRMT; METTL11A; C9orf32; AD-003; HOMT1A; X-Pro-Lys N-Terminal Protein Methyltransferase 1A; Alpha N-Terminal Protein Methyltransferase 1A; Methyltransferase-Like Protein 11A; N-Terminal RCC1 Methyltransferase; NTM1A; Chromosome 9 Open Reading Frame 32; Methyltransferase Like 11A; EC 2.1.1.244 |
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # Q9BV86 Human N-terminal Xaa-Pro-Lys N-methyltransferase 1 |
|---|---|
| 基因名称 | NTMT1 |
| 全名 | N-Terminal Xaa-Pro-Lys N-Methyltransferase 1 |
| 背景介绍 | The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1; MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200). |
| 生物功能 | Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by NTMT2-mediated monomethylation. |
| 细胞定位 | Nucleus |
| 预测分子量 | 25 kDa |
| 翻译后修饰 | Acetylation |
ARG44165 anti-METTL11A antibody IHC-P image
Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG44165 anti-METTL11A antibody at 2 μg/mL dilution.
ARG44165 anti-METTL11A antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG44165 anti-METTL11A antibody at 5 μg/mL dilution.
ARG44165 anti-METTL11A antibody WB image
Western blot: 293T, Hela and A549 stained with ARG44165 anti-METTL11A antibody at 0.5 μg/mL dilution.
ARG44165 anti-METTL11A antibody FACS image
Flow Cytometry: HepG2 stained with ARG44165 anti-METTL11A antibody at 1 μg/1x10^6 cells dilution.
ARG44165 anti-METTL11A antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44165 anti-METTL11A antibody at 2 μg/mL dilution.
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