anti-MHC Class I antibody [2G5] (FITC)

Key features and details

  • 产品描述: FITC-conjugated Mouse Monoclonal antibody [2G5] recognizes MHC Class I.Mouse anti Mouse MHC Class I antibody, clone 2G5 recognizes a monomorphic epitope present on murine MHC class I molecules, expressed at varying levels on the majority of nucleated cells. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region.The epitope recognised by clone 2G5 is conformation dependent and is reported to be phylogenetically conserved (Claesson et al. 1994). Reactivity has been observed with some canine samples suggesting that this antibody may recognize a polymorphic epitope of canine MHC class I.
  • 反应物种: Hu, Ms, Rat, Bov, Gpig, Hm, Pig, Sheep
  • 应用: FACS
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 2G5
  • 同位型: IgG2b
  • 靶点名称: MHC Class I
  • 抗原物种: Mouse
  • Brand:
CAT.NO. : ARG23530
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Product Details
概述
产品描述FITC-conjugated Mouse Monoclonal antibody [2G5] recognizes MHC Class I.
Mouse anti Mouse MHC Class I antibody, clone 2G5 recognizes a monomorphic epitope present on murine MHC class I molecules, expressed at varying levels on the majority of nucleated cells. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region.The epitope recognised by clone 2G5 is conformation dependent and is reported to be phylogenetically conserved (Claesson et al. 1994). Reactivity has been observed with some canine samples suggesting that this antibody may recognize a polymorphic epitope of canine MHC class I.
反应物种Hu, Ms, Rat, Bov, Gpig, Hm, Pig, Sheep
应用FACS
宿主Mouse
克隆Monoclonal
克隆号2G5
同位型IgG2b
靶点名称MHC Class I
抗原物种Mouse
抗原Purified H-2Kb and H-2Db MHC-I molecules.
偶联标记FITC
应用说明
应用建议
应用推荐稀释比
FACS1:10 - 1:25
应用说明FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS, 0.09% Sodium azide and 1% BSA.
抗菌剂0.09% Sodium azide
稳定剂1% BSA
浓度0.1 mg/ml
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
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