anti-MHC Class II antibody [PF6J-6D]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [PF6J-6D] recognizes MHC Class II.Mouse anti Cat MHC Class II antibody, clone PF6J-6D recognizes an epitope within the ~29-31 kDa beta chain region of cat MHC class II molecules which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In cats, this is referred to as the feline leukocyte antigen (FLA) region.The complex retrovirus FIV (feline immunodeficiency virus), is responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency virus (HIV), the intensity of MHC Class II expression on cat lymphocyte membranes has been found to vary in association with feline retrovirus infections.
  • 反应物种: Cat
  • 应用: ELISA, FACS, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: PF6J-6D
  • 同位型: IgG2b
  • 靶点名称: MHC Class II
  • 抗原物种: Cat
  • Brand:
CAT.NO. : ARG23490
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Product Details
概述
产品描述Mouse Monoclonal antibody [PF6J-6D] recognizes MHC Class II.
Mouse anti Cat MHC Class II antibody, clone PF6J-6D recognizes an epitope within the ~29-31 kDa beta chain region of cat MHC class II molecules which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In cats, this is referred to as the feline leukocyte antigen (FLA) region.The complex retrovirus FIV (feline immunodeficiency virus), is responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency virus (HIV), the intensity of MHC Class II expression on cat lymphocyte membranes has been found to vary in association with feline retrovirus infections.
反应物种Cat
应用ELISA, FACS, WB
宿主Mouse
克隆Monoclonal
克隆号PF6J-6D
同位型IgG2b
靶点名称MHC Class II
抗原物种Cat
偶联标记Un-conjugated
应用说明
应用建议
应用推荐稀释比
ELISAAssay-dependent
FACSAssay-dependent
WBAssay-dependent
应用说明WB: This product detects bands of approximately 29-31 kDa on fractionated cat lymphocyte cell lysates under non-reducing conditions.
FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS and 0.05% Sodium azide.
抗菌剂0.05% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
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