anti-MHC Class II antibody [PF6J-6D]
CAT.NO. : ARG23490
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概述
产品描述 | Mouse Monoclonal antibody [PF6J-6D] recognizes MHC Class II. Mouse anti Cat MHC Class II antibody, clone PF6J-6D recognizes an epitope within the ~29-31 kDa beta chain region of cat MHC class II molecules which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In cats, this is referred to as the feline leukocyte antigen (FLA) region.The complex retrovirus FIV (feline immunodeficiency virus), is responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency virus (HIV), the intensity of MHC Class II expression on cat lymphocyte membranes has been found to vary in association with feline retrovirus infections. |
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反应物种 | Cat |
应用 | ELISA, FACS, WB |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | PF6J-6D |
同位型 | IgG2b |
靶点名称 | MHC Class II |
抗原物种 | Cat |
偶联标记 | Un-conjugated |
应用说明
应用建议 |
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应用说明 | WB: This product detects bands of approximately 29-31 kDa on fractionated cat lymphocyte cell lysates under non-reducing conditions. FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein A. |
缓冲液 | PBS and 0.05% Sodium azide. |
抗菌剂 | 0.05% Sodium azide |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
