anti-Midkine antibody (Biotin)

Key features and details

  • 产品描述: Biotin-conjugated Rabbit Polyclonal antibody recognizes Midkine
  • 反应物种: Hu
  • 应用: ELISA, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Midkine
  • 抗原物种: Human
  • 抗原: E.coli derived Recombinant Human Midkine.(VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI RVTKPCTPKT KAKAKAKKGK GKD)
  • Brand:
CAT.NO. : ARG56812
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Product Details
概述
产品描述Biotin-conjugated Rabbit Polyclonal antibody recognizes Midkine
反应物种Hu
应用ELISA, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Midkine
抗原物种Human
抗原E.coli derived Recombinant Human Midkine.
(VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI RVTKPCTPKT KAKAKAKKGK GKD)
偶联标记Biotin
別名ARAP; Neurite outgrowth-promoting protein; Midkine; MK; Neurite outgrowth-promoting factor 2; Amphiregulin-associated protein; Midgestation and kidney protein; NEGF2
应用说明
应用建议
应用推荐稀释比
ELISADirect: 0.25 - 1.0 µg/ml
Sandwich: 0.25 - 1.0 µg/ml with ARG56703 as a capture antibody
WB0.1 - 0.2 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified by affinity chromatography.
缓冲液PBS (pH 7.2)
浓度1 mg/ml
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4192 Human MDK

Swiss-port # P21741 Human Midkine

基因名称MDK
全名midkine (neurite growth-promoting factor 2)
背景介绍This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]
生物功能Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity). [UniProt]
预测分子量16 kDa
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