anti-MLLT10 / AF10 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44233
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MLLT10 / AF10 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MLLT10 / AF10 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human MLLT10 / AF10 |
| 偶联标记 | Un-conjugated |
| Protein Full name | Protein AF-10 |
| 別名 | MLLT10; MLLT10 Histone Lysine Methyltransferase DOT1L Cofactor; AF10; Myeloid/Lymphoid Or Mixed-Lineage Leukemia; Translocated To, 10; ALL1-Fused Gene From Chromosome 10 Protein; Protein AF-10; Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax (Drosophila) Homolog); Translocated To, 10; Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated To, 10; Type III AF10 Protein; Type IV AF10 Protein; Type I AF10 Protein |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MLLT10 |
| 全名 | Mllt10 Histone Lysine Methyltransferase Dot1L Cofactor |
| 背景介绍 | This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation. |
| 细胞定位 | Nucleus |
| 预测分子量 | 113 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation |
检测图片 (3)
ARG44233 anti-MLLT10 / AF10 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG44233 anti-MLLT10 / AF10 antibody at 5 μg/ml dilution.
ARG44233 anti-MLLT10 / AF10 antibody WB image
Western blot: Rat testis stained with ARG44233 anti-MLLT10 / AF10 antibody at 0.5 μg/mL dilution.
ARG44233 anti-MLLT10 / AF10 antibody WB image
Western blot: Mouse testis stained with ARG44233 anti-MLLT10 / AF10 antibody at 0.5 μg/mL dilution.
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