anti-MMP3 antibody [SL-1 ID3]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [SL-1 ID3] recognizes MMP3
  • 反应物种: Hu
  • 应用: ICC/IF, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: SL-1 ID3
  • 同位型: IgG1
  • 靶点名称: MMP3
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG62555
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Product Details
概述
产品描述Mouse Monoclonal antibody [SL-1 ID3] recognizes MMP3
反应物种Hu
应用ICC/IF, WB
宿主Mouse
克隆Monoclonal
克隆号SL-1 ID3
同位型IgG1
靶点名称MMP3
抗原物种Human
抗原APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1).
偶联标记Un-conjugated
別名Transin-1; CHDS6; EC 3.4.24.17; SL-1; STMY1; Matrix metalloproteinase-3; STR1; STMY; MMP-3; Stromelysin-1
应用说明
应用建议
应用推荐稀释比
ICC/IFAssay-dependent
WB1:400
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Conditioned, serum-free medium from TPA treated human Endometrial cells.
属性
形式Liquid
纯化Purified Antibody
缓冲液1X PBS and 0.1% Sodium azide
抗菌剂0.1% Sodium azide
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4314 Human MMP3

Swiss-port # P08254 Human Stromelysin-1

基因名称MMP3
全名matrix metallopeptidase 3
背景介绍Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
生物功能Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. [UniProt]
研究领域Cancer antibody; Cell Biology and Cellular Response antibody; Signaling Transduction antibody
预测分子量54 kDa
参考文献

克隆号文献

Creation, validation, and quantitative analysis of protein expression in vascular tissue microarrays.

IHC / Human

Halushka MK et al.
Cardiovasc Pathol.,  (2010)

publication_link

 

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