anti-MOSC1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes MOSC1
  • 反应物种: Ms
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: MOSC1
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human MOSC1.
  • Brand:
CAT.NO. : ARG42605
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes MOSC1
反应物种Ms
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称MOSC1
抗原物种Human
抗原Synthetic peptide derived from Human MOSC1.
偶联标记Un-conjugated
別名Mitochondrial amidoxime-reducing component 1; EC 1.-.-.-; MOSC domain-containing protein 1; MOSC1; Molybdenum cofactor sulfurase C-terminal domain-containing protein 1; Moco sulfurase C-terminal domain-containing protein 1; mARC1
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照NIH/3T3
实际分子量~ 37 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol and 0.5% BSA
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 66112 MouseMARC1

GeneID: 72925 MouseMARC1

Swiss-port # Q6NZQ8 Mouse E3 ubiquitin-protein ligase MARCH1

Swiss-port # Q9CW42 Mouse Mitochondrial amidoxime-reducing component 1

基因名称MARC1
全名mitochondrial amidoxime reducing component 1
生物功能Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed:19053771, PubMed:21029045, PubMed:30397129). As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability (PubMed:19053771). May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis (PubMed:21029045). Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction (PubMed:21029045, PubMed:19053771). [UniProt]
细胞定位Mitochondrion outer membrane; Single-pass type II membrane protein. Membrane; Lipid-anchor. Note=Mitochondrial import is mediated by AA 1-40 and requires ATP. [UniProt]
预测分子量37 kDa
检测图片 (1)
  • ARG42605 anti-MOSC1 antibody WB image

    Western blot: NIH/3T3 cell lysate stained with ARG42605 anti-MOSC1 antibody at 1:1000 diluiton, overnight at 4°C.

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