anti-MPO / Myeloperoxidase antibody

Key features and details

  • 产品描述: Mouse Polyclonal antibody recognizes MPO / Myeloperoxidase
  • 反应物种: Hu, Ms
  • 应用: IHC-P
  • 宿主: Mouse
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: MPO / Myeloperoxidase
  • 抗原物种: Human
  • 抗原: Synthetic peptide of Human MPO / Myeloperoxidase.
  • Brand:
CAT.NO. : ARG66954
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Product Details
概述
产品描述Mouse Polyclonal antibody recognizes MPO / Myeloperoxidase
反应物种Hu, Ms
应用IHC-P
宿主Mouse
克隆Polyclonal
同位型IgG
靶点名称MPO / Myeloperoxidase
抗原物种Human
抗原Synthetic peptide of Human MPO / Myeloperoxidase.
偶联标记Un-conjugated
Protein Full nameMyeloperoxidase
別名MPO; Myeloperoxidase; EC 1.11.2.2; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Human Lung
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol and 0.5% BSA
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 17523 Mouse MPO

GeneID: 4353 Human MPO

Swiss-port # P05164 Human Myeloperoxidase

Swiss-port # P11247 Mouse Myeloperoxidase

基因名称MPO
全名myeloperoxidase
背景介绍Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
生物功能Myeloperoxidase (MPO): Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt]
细胞定位Lysosome. [UniProt]
产品亮点Related Antibody Duos and Panels:
ARG30325 Inflammatory Cell Antibody Panel
Related products:
MPO antibodies; MPO ELISA Kits; MPO Duos / Panels; Anti-Mouse IgG secondary antibodies;
Related news:
Exploring Antiviral Immune Response
研究领域Inflammatory Cell Marker antibody; Neurophil Marker antibody
预测分子量60 kDa, 84 kDa, 89 kDa
检测图片 (1)
  • ARG66954 anti-MPO / Myeloperoxidase antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human lung tissue stained with ARG66954 anti-MPO / Myeloperoxidase antibody at 1:200 dilution (4°C, overnight).

参考文献

Trimebutine prevents corneal inflammation in a rat alkali burn model

IHC-P / Rat

Hitoshi Goto et al.
Sci Rep.,  (2024)

publication_link

 

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