anti-MPZL1 antibody
CAT.NO. : ARG44206
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MPZL1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MPZL1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human MPZL1 |
| 偶联标记 | Un-conjugated |
| Protein Full name | Myelin protein zero-like protein 1 |
| 別名 | GeneCards Symbol: MPZL1; Myelin Protein Zero Like 1; PZR; Myelin Protein Zero-Like Protein 1; FLJ21047; Immunoglobulin Family Transmembrane Protein; Protein Zero Related; Protein Zero-Related; MPZL1b; PZR1b; PZRa; PZRb |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O95297 Human Myelin protein zero-like protein 1 |
|---|---|
| 基因名称 | MPZL1 |
| 全名 | Myelin Protein Zero Like 1 |
| 背景介绍 | Predicted to enable structural molecule activity. Predicted to be involved in cell-cell signaling and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within positive regulation of cell migration. Located in cell surface and focal adhesion. |
| 生物功能 | Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility. |
| 细胞定位 | Membrane |
| 预测分子量 | 29 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein |
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