anti-MRGPRX1 / MRGX1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG59834
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MRGPRX1 / MRGX1 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MRGPRX1 / MRGX1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 263-322 of Human MRGPRX1 (NP_671732.3). |
| 偶联标记 | Un-conjugated |
| 別名 | SNSR4; MRGX1; MGRG2; Sensory neuron-specific G-protein coupled receptor 3/4; GPCR; Mas-related G-protein coupled receptor member X1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Rat liver and Mouse liver | ||||
| 实际分子量 | 36 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8CIP3 Mouse Mas-related G-protein coupled receptor member X1 |
|---|---|
| 基因名称 | MRGPRX1 |
| 全名 | MAS-related GPR, member X1 |
| 生物功能 | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 36 kDa |
检测图片 (1)
ARG59834 anti-MRGPRX1 / MRGX1 antibody WB image
Western blot: 25 µg of Rat liver and Mouse liver lysates stained with ARG59834 anti-MRGPRX1 / MRGX1 antibody at 1:3000 dilution.
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