anti-MSH4 antibody
CAT.NO. : ARG40450
US$ Please choose
US$ Please choose
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概述
产品描述 | Rabbit Polyclonal antibody recognizes MSH4 |
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反应物种 | Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | MSH4 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 697-936 of Human MSH4 (NP_002431.2). |
偶联标记 | Un-conjugated |
別名 | MutS protein homolog 4; hMSH4 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Mouse skeletal muscle | ||||
实际分子量 | 105 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | MSH4 |
全名 | mutS homolog 4 |
背景介绍 | This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. [provided by RefSeq, Aug 2011] |
生物功能 | Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis. [UniProt] |
预测分子量 | 105 kDa |
