anti-Mucin 5AC antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Mucin 5AC
  • 反应物种: Hu
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Mucin 5AC
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human Mucin 5AC.
  • Brand:
CAT.NO. : ARG59705
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Mucin 5AC
反应物种Hu
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Mucin 5AC
抗原物种Human
抗原Synthetic peptide derived from Human Mucin 5AC.
偶联标记Un-conjugated
別名leB; Major airway glycoprotein; Lewis B blood group antigen; Tracheobronchial mucin; mucin; Mucin-5AC; LeB; MUC5; TBM; Gastric mucin; MUC-5AC; Mucin-5 subtype AC, tracheobronchial
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量220 - 600 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4586 Human MUC5AC

基因名称MUC5AC
全名mucin 5AC, oligomeric mucus/gel-forming
生物功能Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. [UniProt]
细胞定位Secreted. [UniProt]
预测分子量586 kDa
翻译后修饰C-, O- and N-glycosylated. O-glycosylated on the Thr-/Ser-rich tandem repeats. C-mannosylation in the Cys-rich subdomains may be required for proper folding of these regions and for export from the endoplasmic reticulum during biosynthesis.

Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease. The extent of cleavage is increased in the acidic parts of the secretory pathway. Cleavage generates a reactive group which could link the protein to a primary amide. [UniProt]
检测图片 (1)
  • ARG59705 anti-Mucin 5AC antibody WB image

    Western blot: Human stomach lysate stained with ARG59705 anti-Mucin 5AC antibody.

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