anti-Munc18-1 phospho (Ser241) antibody
Key features and details
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- 预测物种:
- 应用:
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- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG52342
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Munc18-1 phospho (Ser241) |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu, Rat, Bov, Chk, Dog, NHuPrm, Sheep |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Munc18-1 |
| 抗原物种 | Mouse |
| 抗原 | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser241 conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | p67; Unc18-1; Protein unc-18 homolog A; MUNC18-1; RBSEC1; NSEC1; Protein unc-18 homolog 1; UNC18; Unc-18A; P67; Syntaxin-binding protein 1; N-Sec1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | Specific for the ~65k Munc18-1 protein phosphorylated at Ser241. Immunolabeling is blocked by the treatment of the lysate with lambda phosphatase (30 minutes, 800 units / 1 mg protein). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | STXBP1 |
| 全名 | syntaxin binding protein 1 |
| 背景介绍 | Munc-18 (mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc18-1 is thought to be regulated by phosphorylation. |
| 研究领域 | Cancer antibody; Metabolism antibody; Neuroscience antibody |
| 预测分子量 | 68 kDa |
检测图片 (1)
ARG52342 anti-Munc18-1 phospho (Ser241) antibody WB image
Western blot: Mouse hippocampus lysate showing specific immunolabeling of the ~65k Munc18-1 protein phosphorylated at Ser 241 stained with ARG52342 anti-Munc18-1 phospho (Ser241) antibody.
Phosphospecificity is shown in the second lane where immunolabeling is blocked by treatment of the lysate with lambda phosphatase (P-tase).
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