anti-MyD88 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes MyD88
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Dog
  • 应用: ELISA, IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: MyD88
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63727
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes MyD88
反应物种Hu
预测物种Ms, Rat, Dog
应用ELISA, IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称MyD88
抗原物种Human
抗原C-IKYKAMKKEFP
偶联标记Un-conjugated
別名MYD88D; Myeloid differentiation primary response protein MyD88
应用说明
应用建议
应用推荐稀释比
ELISA5 - 10 µg/ml (detection Ab)
IHC-P4 - 6 µg/ml
WB0.1 - 0.3 µg/ml
应用说明IHC-P: Antigen Retrieval: Steam tissue section in Tris/EDTA buffer (pH 9.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4615 Human MYD88

Swiss-port # Q99836 Human Myeloid differentiation primary response protein MyD88

背景介绍This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
产品亮点Related products:
MYD88 antibodies; Anti-Goat IgG secondary antibodies;
Related poster download:
Toll-like Receptor.pdf
研究领域Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody
预测分子量33 kDa
检测图片 (2)
  • ARG63727 anti-MyD88 antibody IHC-P image

    Immunohistochemistry: Paraffin embedded Human Tonsil. (Steamed antigen retrieval with Tris/EDTA buffer pH 9) stained with ARG63727 anti-MyD88 antibody at 4 µg/ml dilution followed by HRP-staining. These results could not been obtained after antigen retireval at pH6 with this batch of antibody.

  • ARG63727 anti-MyD88 antibody WB image

    Western blot: 35 µg of Human thymus lysate (in RIPA buffer) stained with ARG63727 anti-MyD88 antibody at 0.2 µg/ml dilution and incubated at RT for 1 hour.

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