anti-Myelin Basic Protein antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Goat Polyclonal antibody recognizes Myelin Basic Protein |
|---|---|
| 反应物种 | Hu, Ms, Rat, Cow, Pig |
| 应用 | IHC-Fr, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Myelin Basic Protein |
| 抗原物种 | Bovine |
| 抗原 | Purified Myelin Basic Protein isolated from bovine brain. |
| 偶联标记 | Un-conjugated |
| 別名 | MBL; Mannose-binding lectin; HSMBPC; Mannose-binding protein C; MBP1; COLEC1; MBL2D; MBP-C; Mannan-binding protein; Collectin-1; MBP; MBPD |
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 5 mM Sodium azide and 50% Glycerol. |
| 抗菌剂 | 5 mM Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
|---|---|
| 基因名称 | MBL2 |
| 全名 | mannose-binding lectin (protein C) 2, soluble |
| 背景介绍 | This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008] |
| 生物功能 | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 26 kDa |
ARG11119 anti-Myelin Basic Protein antibody IHC-Fr image
Immunohistochemistry: Frozen section of Mouse hippocampus tissue stained with ARG11119 anti-Myelin Basic Protein antibody (red) at 1:5000 dilution, and co-stained with anti-GFAP antibody (green) at 1:5000 dilution. Hoechst (blue) for nuclear staining.
ARG11119 anti-Myelin Basic Protein antibody WB image
Western blot: Rat cerebellum, Mouse cerebellum, Cow midbrain and Pig midbrain lysates stained with ARG11119 anti-Myelin Basic Protein antibody at 1:5000 dilution.
Multiple bands between 15-25 kDa mark correspond to the various alternate transcripts of the single MBP gene.
ARG11119 anti-Myelin Basic Protein antibody IHC-Fr image
Immunohistochemistry: Frozen section of Rat cerebellum tissue stained with ARG11119 anti-Myelin Basic Protein antibody (red) at 1:5000 dilution, and co-stained with anti-GFAP antibody (green) at 1:5000 dilution.
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