anti-MYO5A antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes MYO5A
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: MYO5A
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 950-1150 of Human MYO5A (NP_000250.3).
  • Brand:
CAT.NO. : ARG41405
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes MYO5A
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称MYO5A
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 950-1150 of Human MYO5A (NP_000250.3).
偶联标记Un-conjugated
別名GS1; MYH12; Unconventional myosin-Va; MYR12; Myosin-12; MYO5; Dilute myosin heavy chain, non-muscle; Myoxin; Myosin heavy chain 12
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照MCF7
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 17918 Mouse MYO5A

GeneID: 25017 Rat MYO5A

GeneID: 4644 Human MYO5A

基因名称MYO5A
全名myosin VA
背景介绍This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. [provided by RefSeq, Dec 2008]
生物功能Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation. [UniProt]
预测分子量215 kDa
检测图片 (1)
  • ARG41405 anti-MYO5A antibody WB image

    Western blot: 25 µg of MCF7 cell lysate stained with ARG41405 anti-MYO5A antibody at 1:1000 dilution.

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