anti-N-Ras antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG44024
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Size:
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes N-RAS |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Pig |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | N-RAS |
| 抗原物种 | Human |
| 抗原 | Human N-RAS recombinantprotein |
| 偶联标记 | Un-conjugated |
| Protein Full name | GTPase Nras |
| 別名 | NRAS; NRAS Proto-Oncogene, GTPase; N-Ras; Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog; Neuroblastoma RAS Viral Oncogene Homolog; Transforming Protein N-Ras; GTPase NRas; V-Ras Neuroblastoma RAS Viral Oncogene Homolog; Proto-Oncogene GTPase; N-Ras Protein Part 4; EC 3.6.5.2; ALPS4; NRAS1; HRAS1; CMNS; KRAS; NCMS; NS6 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS containing 0.02% sodium azide |
| 抗菌剂 | 0.02% sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NRAS |
| 全名 | NRAS Proto-Oncogene, GTPase |
| 背景介绍 | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. |
| 生物功能 | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. |
| 细胞定位 | Cell membrane, Golgi apparatus, Membrane |
| 预测分子量 | 21 kDa |
| 翻译后修饰 | Acetylation, Glycoprotein, Isopeptide bond, Lipoprotein, Methylation, Palmitate, Phosphoprotein, Prenylation, Ubl conjugation |
检测图片 (1)
ARG44024 anti-N-Ras antibody WB image
Western blot: A431 stained with ARG44024 anti-N-Ras antibody at 2 μg/mL dilution.
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