anti-NACA1 + NACA2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes NACA1 + NACA2
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NACA1 + NACA2
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 1-215 of Human NACA1 (NP_001106673.1).
  • Brand:
CAT.NO. : ARG40460
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes NACA1 + NACA2
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NACA1 + NACA2
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 1-215 of Human NACA1 (NP_001106673.1).
偶联标记Un-conjugated
別名NACA1; Alpha-NAC, muscle-specific form; HSD48; skNAC; Nascent polypeptide-associated complex subunit alpha, muscle-specific form
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照U-87MG
实际分子量~ 38 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 17938 Mouse NACA

GeneID: 4666 Human NACA

Swiss-port # P70670 Mouse Nascent polypeptide-associated complex subunit alpha, muscle-specific form

Swiss-port # Q13765 Human Nascent polypeptide-associated complex subunit alpha

基因名称NACA
全名nascent polypeptide-associated complex alpha subunit
背景介绍The protein encoded by this gene associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). NAC binds to nascent proteins as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. However, nascent proteins with an exposed signal peptide will not be bound by the encoded protein, enabling them to bind the SRP and enter the secretory pathway. This protein has been determined to be an IgE autoantigen in atopic dermatitis patients. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
生物功能Cardiac- and muscle-specific transcription factor. May act to regulate the expression of genes involved in the development of myotubes. Plays a critical role in ventricular cardiomyocyte expansion and regulates postnatal skeletal muscle growth and regeneration. Involved in the organized assembly of thick and thin filaments of myofibril sarcomeres (By similarity). [UniProt]
细胞定位Cytoplasm. Nucleus. [UniProt]
预测分子量205 kDa
检测图片 (1)
  • ARG40460 anti-NACA1 + NACA2 antibody WB image

    Western blot: 25 µg of U-87MG cell lysate stained with ARG40460 anti-NACA1 + NACA2 antibody at 1:1000 dilution.

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