anti-NBL1 antibody [38G8]

CAT.NO. : ARG57025

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [38G8] recognizes NBL1
反应物种	Hu
应用	FACS, ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	38G8
同位型	IgG1, kappa
靶点名称	NBL1
抗原物种	Human
抗原	Recombinant fragment around aa. 18-181 of Human NBL1.
偶联标记	Un-conjugated
別名	NB; DAN; NO3; DAND1; D1S1733E

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 4681 Human NBL1 Swiss-port # P41271 Human Neuroblastoma suppressor of tumorigenicity 1
基因名称	NBL1
全名	neuroblastoma 1, DAN family BMP antagonist
背景介绍	This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
生物功能	Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process. [UniProt]
预测分子量	19 kDa

检测图片 (5)

ARG57025 anti-NBL1 antibody [38G8] ICC/IF image
Immunoflorescense: Jurkat cell line stained with ARG57025 anti-NBL1 antibody [38G8] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
ARG57025 anti-NBL1 antibody [38G8] FACS image
Flow Cytometry: Jurkat cell line stained with ARG57025 anti-NBL1 antibody [38G8] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).
ARG57025 anti-NBL1 antibody [38G8] WB image
Western blot: 30 µg of Jurkat cell lysate stained with ARG57025 anti-NBL1 antibody [38G8] at 1:1000.
ARG57025 anti-NBL1 antibody [38G8] ICC/IF image
Immunoflorescense: A549 cell line stained with ARG57025 anti-NBL1 antibody [38G8] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
ARG57025 anti-NBL1 antibody [38G8] FACS image
Flow Cytometry: A549 cell line stained with ARG57025 anti-NBL1 antibody [38G8] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).

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