anti-NCOA5 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44094
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Product Details
概述
| 产品描述 | Rabbit Polyclonal recognizes NCOA5 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NCOA5 |
| 抗原物种 | Human |
| 抗原 | Human NCOA5 recombinant protein (Position: R191-Q560). |
| 偶联标记 | Un-conjugated |
| 別名 | NCOA5; Nuclear Receptor Coactivator 5; CIA; Coactivator Independent Of AF-2; BA465L10.6; NCoA-5; KIAA1637 |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NCOA5 |
| 全名 | Nuclear Receptor Coactivator 5 |
| 背景介绍 | This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Several alternatively spliced transcript variants have been found for this gene. |
| 生物功能 | Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2). |
| 细胞定位 | Nucleus |
| 预测分子量 | 66 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (5)
ARG44094 anti-NCOA5 antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG44094 anti-NCOA5 antibody at 5 μg/ml dilution.
ARG44094 anti-NCOA5 antibody WB image
Western blot: 293T and Hela stained with ARG44094 anti-NCOA5 antibody at 0.5 μg/mL dilution.
ARG44094 anti-NCOA5 antibody FACS image
Flow Cytometry: HeLa stained with ARG44094 anti-NCOA5 antibody at 1 µg/10^6 cells dilution.
ARG44094 anti-NCOA5 antibody WB image
Western blot: Rat brain stained with ARG44094 anti-NCOA5 antibody at 0.5 μg/mL dilution.
ARG44094 anti-NCOA5 antibody WB image
Western blot: Mouse brain and Mouse thymus stained with ARG44094 anti-NCOA5 antibody at 0.5 μg/mL dilution.
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