anti-NDUFA13 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes NDUFA13
  • 反应物种: Hu, Ms
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NDUFA13
  • 抗原物种: Human
  • 抗原: Fusion protein of human NDUFA13
  • Brand:
CAT.NO. : ARG65563
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes NDUFA13
反应物种Hu, Ms
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NDUFA13
抗原物种Human
抗原Fusion protein of human NDUFA13
偶联标记Un-conjugated
別名CI-B16.6; NADH-ubiquinone oxidoreductase B16.6 subunit; CGI-39; Gene associated with retinoic and interferon-induced mortality 19 protein; Cell death regulatory protein GRIM-19; Complex I-B16.6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; GRIM19; CDA016; B16.6; GRIM-19; Gene associated with retinoic and IFN-induced mortality 19 protein
应用说明
应用建议
应用推荐稀释比
IHC-P50-200
WB500-2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse spleen and skeletal muscle tissue, Human hepatocellular carcinoma, Mouse liver and Human placenta tissue, HeLa and 293T cell tissue.
属性
形式Liquid
纯化Purified by antigen-affinity chromatography.
缓冲液1XPBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol
抗菌剂0.05% Sodium azide
稳定剂40% Glycerol
浓度2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 51079 Human NDUFA13

GeneID: 67184 Mouse NDUFA13

Swiss-port # Q9ERS2 Mouse NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

Swiss-port # Q9P0J0 Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

基因名称NDUFA13
全名NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
背景介绍This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.
生物功能Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes. [UniProt]
产品亮点Related products:
Anti-Rabbit IgG secondary antibodies;
Related poster download:
The Structure & Functions of Mitochondria.pdf
研究领域Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody
预测分子量17 kDa
检测图片 (3)
  • ARG65563 anti-NDUFA13 antibody WB image

    Western blot: 40 μg of 1) Mouse spleen, 2) Mouse skeletal muscle, 3) Human hepatocellular carcinoma, 4) Mouse liver, 5) Human placenta, 6) HeLa, and 7) 293T lysates stained with ARG65563 anti-NDUFA13 antibody at 1:350 dilution. Exposure time: 30 seconds.

  • ARG65563 anti-NDUFA13 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human ovarian cancer tissue stained with ARG65563 anti-NDUFA13 antibody (left) at 1:40 dilution, or the same antibody preincubated with fusion protein (right). (Original magnification: X200).

  • ARG65563 anti-NDUFA13 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human ovarian cancer tissue stained with ARG65563 anti-NDUFA13 antibody (left) at 1:40 dilution, or the same antibody preincubated with fusion protein (right). (Original magnification: X200).

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