anti-NDUFAF4 antibody
产品描述 | Rabbit Polyclonal antibody recognizes NDUFAF4 |
---|---|
反应物种 | Hu |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | NDUFAF4 |
抗原物种 | Human |
抗原 | Synthetic peptide of human NDUFAF4 |
偶联标记 | Un-conjugated |
別名 | HSPC125; C6orf66; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4; Hormone-regulated proliferation-associated protein of 20 kDa; HRPAP20; bA22L21.1; My013 |
应用建议 |
| ||||||
---|---|---|---|---|---|---|---|
应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Raji cell |
形式 | Liquid |
---|---|
纯化 | Purified by antigen-affinity chromatography. |
缓冲液 | 1XPBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 40% Glycerol |
浓度 | 2.8 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
数据库连接 | Swiss-port # Q9P032 Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 |
---|---|
基因名称 | NDUFAF4 |
全名 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
背景介绍 | NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency. |
生物功能 | Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion. [UniProt] |
产品亮点 | Related products: Anti-Rabbit IgG secondary antibodies; Related poster download: The Structure & Functions of Mitochondria.pdf |
研究领域 | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
预测分子量 | 20 kDa |
翻译后修饰 | Phosphorylated on serine. Prolactin stimulate serine phosphorylation (By similarity). |
ARG65572 anti-NDUFAF4 antibody WB image
Western blot: 40 μg of Raji cell lysate stained with ARG65572 anti-NDUFAF4 antibody at 1:300 dilution. Exporsure time: 5 seconds.
ARG65572 anti-NDUFAF4 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human ovarian cancer tissue stained with ARG65572 anti-NDUFAF4 antibody (left) at 1:45 dilution, or the same antibody preincubated with synthetic peptide (right). (Original magnification: ×200).
ARG65572 anti-NDUFAF4 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human ovarian cancer tissue stained with ARG65572 anti-NDUFAF4 antibody (left) at 1:45 dilution, or the same antibody preincubated with synthetic peptide (right). (Original magnification: ×200).
