anti-NDUFS8 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes NDUFS8
  • 反应物种: Hu, Ms
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NDUFS8
  • 抗原物种: Human
  • 抗原: Fusion protein of human NDUFS8
  • Brand:
CAT.NO. : ARG65578
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes NDUFS8
反应物种Hu, Ms
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NDUFS8
抗原物种Human
抗原Fusion protein of human NDUFS8
偶联标记Un-conjugated
別名EC 1.6.5.3; TYKY; NADH-ubiquinone oxidoreductase 23 kDa subunit; CI-23k; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; CI23KD; Complex I-23kD; EC 1.6.99.3; CI-23kD; TYKY subunit
应用说明
应用建议
应用推荐稀释比
IHC-P25-100
WB500-2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Jurkat cell, mouse heart and brain tissue
属性
形式Liquid
纯化Purified by antigen-affinity chromatography.
缓冲液1XPBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol
抗菌剂0.05% Sodium azide
稳定剂40% Glycerol
浓度0.9 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 225887 Mouse NDUFS8

GeneID: 4728 Human NDUFS8

Swiss-port # O00217 Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

Swiss-port # Q8K3J1 Mouse NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

基因名称NDUFS8
全名NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
背景介绍This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.
生物功能Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone. [UniProt]
产品亮点Related products:
NDUFS8 antibodies; Anti-Rabbit IgG secondary antibodies;
Related poster download:
The Structure & Functions of Mitochondria.pdf
研究领域Cancer antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
预测分子量24 kDa
检测图片 (3)
  • ARG65578 anti-NDUFS8 antibody WB image

    Western blot: 40 μg of 1) Jurkat, 2) Mouse heart, and 3) Mouse brain lysates stained with ARG65578 anti-NDUFS8 antibody at 1:250 dilution. Exposure time: 20 seconds.

  • ARG65578 anti-NDUFS8 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human thyroid cancer tissue stained with ARG65578 anti-NDUFS8 antibody (left) at 1:20 dilution, or the same antibody preincubated with fusion protein (right). (Original magnification: ×200).

  • ARG65578 anti-NDUFS8 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human thyroid cancer tissue stained with ARG65578 anti-NDUFS8 antibody (left) at 1:20 dilution, or the same antibody preincubated with fusion protein (right). (Original magnification: ×200).

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