anti-NEDD1 antibody
CAT.NO. : ARG64078
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概述
产品描述 | Goat Polyclonal antibody recognizes NEDD1 |
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反应物种 | Hu |
应用 | WB |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | NEDD1 |
抗原物种 | Human |
抗原 | C-NQTRNSEKFEKPEN |
偶联标记 | Un-conjugated |
別名 | GCP-WD; Protein NEDD1; NEDD-1; Neural precursor cell expressed developmentally down-regulated protein 1; TUBGCP7 |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | NEDD1 |
全名 | neural precursor cell expressed, developmentally down-regulated 1 |
生物功能 | Required for mitosis progression. Promotes the nucleation of microtubules from the spindle. [UniProt] |
研究领域 | Cell Biology and Cellular Response antibody; Developmental Biology antibody; Gene Regulation antibody |
预测分子量 | 72 kDa |
翻译后修饰 | During mitosis, prior phosphorylation on Thr-550 by CDK1 promotes subsequent phosphorylation by PLK1 on Thr-382, Ser-397, Ser-426 and Ser-637. Phosphorylated NEDD1 can interact with gamma-tubulin for targeting the gamma-tubulin ring complex (gTuRC) to the centrosome, an important step for spindle formation. |
