anti-NFE2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes NFE2
  • 反应物种: Hu
  • 应用: ELISA, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NFE2
  • 抗原物种: Human
  • 抗原: Human NFE2 recombinant protein
  • Brand:
CAT.NO. : ARG43906
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes NFE2
反应物种Hu
应用ELISA, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NFE2
抗原物种Human
抗原Human NFE2 recombinant protein
表达系统E.coli
偶联标记Un-conjugated
Protein Full nameTranscription factor NF-E2 45 kDa subunit
別名NFE2; Nuclear Factor, Erythroid 2; NF-E2; Nuclear Factor, Erythroid-Derived 2 45 KDa Subunit; Transcription Factor NF-E2 45 KDa Subunit; Leucine Zipper Protein NF-E2; P45 NF-E2; P45
应用说明
应用建议
应用推荐稀释比
ELISA0.1-0.5 µg/ml
WB0.25-0.5 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 4778 Human NFE2

Swiss-port # Q16621 Human Transcription factor NF-E2 45 kDa subunit

基因名称NFE2
全名Nuclear Factor, Erythroid 2
背景介绍Enables several functions, including WW domain binding activity; identical protein binding activity; and protein N-terminus binding activity. Contributes to cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of bone mineralization; and negative regulation of syncytium formation by plasma membrane fusion. Part of protein-DNA complex.
生物功能Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
细胞定位Cytoplasm, Nucleus
预测分子量42 kDa
翻译后修饰Isopeptide bond, Phosphoprotein, Ubl conjugation
检测图片 (1)
  • ARG43906 anti-NFE2 antibody WB image

    Western blot: K562 and HepG2 stained with ARG43906 anti-NFE2 antibody at 0.5 μg/mL dilution.

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