anti-NFKBIZ antibody
CAT.NO. : ARG44060
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概述
| 产品描述 | Rabbit Polyclonal recognizes NFKBIZ |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NFKBIZ |
| 抗原物种 | Human |
| 抗原 | Human NFKBIZ recombinant protein (Position: Q247-H577). |
| 偶联标记 | Un-conjugated |
| 別名 | NFKBIZ; NFKB Inhibitor Zeta; MAIL; INAP; IL-1 Inducible Nuclear Ankyrin-Repeat Protein; NF-Kappa-B Inhibitor Zeta; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor, Zeta; Molecule Possessing Ankyrin Repeats Induced By Lipopolysaccharide; I-Kappa-B-Zeta; IkappaBzeta; FLJ34463; IkB-Zeta; IKBZ; IkappaB-Zeta |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NFKBIZ |
| 全名 | NFKB Inhibitor Zeta |
| 背景介绍 | This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR). |
| 细胞定位 | Nucleus |
| 预测分子量 | 78 kDa |
检测图片 (3)
ARG44060 anti-NFKBIZ antibody ICC/IF image
Immunofluorescence: SIHA stained with ARG44060 anti-NFKBIZ antibody at 5 μg/mL dilution.
ARG44060 anti-NFKBIZ antibody WB image
Western blot: RT4 and Caco-2 stained with ARG44060 anti-NFKBIZ antibody at 0.5 μg/mL dilution.
ARG44060 anti-NFKBIZ antibody FACS image
Flow Cytometry: HEL stained with ARG44060 anti-NFKBIZ antibody at 1 µg/1x10^6 cells dilution.
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