anti-NKG2A + C + E antibody [20d5] (FITC)

CAT.NO. : ARG22068

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Size:

250 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	FITC-conjugated Rat Monoclonal antibody [20d5] recognizes NKG2A + C + E
反应物种	Ms
应用	BL, FACS
特异性	Mouse NKG2-A + C + E
宿主	Rat
克隆	Monoclonal
克隆号	20d5
同位型	IgG2a, kappa
靶点名称	NKG2A + C + E
抗原物种	Mouse
抗原	CHO cells transfected with B6 allele of NKG2A gene
偶联标记	FITC
別名	NK cell receptor A; CD159 antigen-like family member A; NKG2-A/NKG2-B type II integral membrane protein; CD159A; CD antigen CD159a; NKG2; NKG2A; NKG2-A/B-activating NK receptor

应用说明

应用建议

应用	推荐稀释比
BL	Assay-dependent
FACS

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
缓冲液	PBS and 0.1% Sodium azide.
抗菌剂	0.1% Sodium azide
浓度	0.5 mg/ml
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称	KLRC1
全名	killer cell lectin-like receptor subfamily C, member 1
背景介绍	Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015]
生物功能	Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. [UniProt]
预测分子量	26 kDa

检测图片 (1)

ARG22068 anti-NKG2A + C + E antibody [20d5] (FITC) FACS image
Flow Cytometry: C57BL/6 Mouse splenocytes stained with ARG22068 anti-NKG2A + C + E antibody [20d5] (FITC) and ARG65527 anti-CD161bc / NK1.1 antibody [PK136] (PE).

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