anti-NNT antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes NNT
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NNT
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 881-1086 of Human NNT (NP_036475.3).
  • Brand:
CAT.NO. : ARG43160
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes NNT
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NNT
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 881-1086 of Human NNT (NP_036475.3).
偶联标记Un-conjugated
別名GCCD4; NAD(P) transhydrogenase, mitochondrial; EC 1.6.1.2; Nicotinamide nucleotide transhydrogenase; Pyridine nucleotide transhydrogenase
应用说明
预测反应性说明Human
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse liver
实际分子量~ 128 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 23530 Human NNT

Swiss-port # Q13423 Human NAD(P) transhydrogenase, mitochondrial

基因名称NNT
全名nicotinamide nucleotide transhydrogenase
背景介绍This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. [provided by RefSeq, Sep 2016]
生物功能The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity). May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland (PubMed:22634753). [UniProt]
细胞定位Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side. [UniProt]
预测分子量114 kDa
检测图片 (1)
  • ARG43160 anti-NNT antibody WB image

    Western blot: 25 µg of Mouse liver lysate stained with ARG43160 anti-NNT antibody at 1:3000 dilution.

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