anti-Nodal antibody
CAT.NO. : ARG43008
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概述
产品描述 | Rabbit Polyclonal antibody recognizes Nodal |
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反应物种 | Hu, Rat |
应用 | FACS, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | Nodal |
抗原物种 | Human |
抗原 | Synthetic peptide of Human Nodal. |
偶联标记 | Un-conjugated |
別名 | Nodal homolog; HTX5 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | HeLa | ||||||
实际分子量 | ~ 40 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
抗菌剂 | 0.01% Sodium azide |
稳定剂 | 40% Glycerol and 0.05% BSA |
浓度 | Batch dependent |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | NODAL |
全名 | nodal growth differentiation factor |
背景介绍 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016] |
生物功能 | Essential for mesoderm formation and axial patterning during embryonic development. [UniProt] |
细胞定位 | Secreted. [UniProt] |
预测分子量 | 40 kDa |
