anti-NOX5 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes NOX5
  • 反应物种: Hu
  • 应用: ICC, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NOX5
  • 抗原物种: Human
  • 抗原: Synthetic peptide corresponding to aa. 747-765 of Human NOX5. (KVLKGHCEKFGFRFFQENF)
  • Brand:
CAT.NO. : ARG59888
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes NOX5
反应物种Hu
应用ICC, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NOX5
抗原物种Human
抗原Synthetic peptide corresponding to aa. 747-765 of Human NOX5. (KVLKGHCEKFGFRFFQENF)
偶联标记Un-conjugated
別名NADPH oxidase 5; EC 1.6.3.-
应用说明
应用建议
应用推荐稀释比
ICC0.5 - 1 µg/ml
IHC-P0.5 - 1 µg/ml
WB0.1 - 0.5 µg/ml
应用说明IHC-P: Antigen Retrieval: Heat mediation was recommended.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量~ 85 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
抗菌剂0.05% Thimerosal and 0.05% Sodium azide
稳定剂5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 79400 Human NOX5

Swiss-port # Q96PH1 Human NADPH oxidase 5

基因名称NOX5
全名NADPH oxidase, EF-hand calcium binding domain 5
背景介绍This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
生物功能Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin. [UniProt]
细胞定位Membrane; Multi-pass membrane protein. Isoform v2: Endoplasmic reticulum. Isoform v5: Endoplasmic reticulum. [UniProt]
预测分子量86 kDa
检测图片 (3)
  • ARG59888 anti-NOX5 antibody ICC image

    Immunocytochemistry: HeLa cells stained with ARG59888 anti-NOX5 antibody.

  • ARG59888 anti-NOX5 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human mammary cancer tissue stained with ARG59888 anti-NOX5 antibody.

  • ARG59888 anti-NOX5 antibody WB image

    Western blot: 40 µg of 22RV1, PANC, HeLa and SKOV whole cell lysates stained with ARG59888 anti-NOX5 antibody at 0.5 µg/ml dilution.

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