anti-NPAS4 antibody [S408-79]
CAT.NO. : ARG23715
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概述
| 产品描述 | Mouse Monoclonal antibody [S408-79] recognizes NPAS4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | S408-79 |
| 同位型 | IgG1 |
| 靶点名称 | NPAS4 |
| 抗原物种 | Rat |
| 抗原 | Fusion protein amino acids 597-802 (C-terminus) of Rat NPAS4. |
| 偶联标记 | Un-conjugated |
| 別名 | PASD10; Neuronal PAS domain-containing protein 4; Class E basic helix-loop-helix protein 79; PAS domain-containing protein 10; HLH-PAS transcription factor NXF; NXF; Le-PAS; bHLHe79; Neuronal PAS4 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 90 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.1% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NPAS4 |
| 全名 | neuronal PAS domain protein 4 |
| 背景介绍 | NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene. [UniProt] |
| 细胞定位 | Nucleus [UniProt] |
| 预测分子量 | 87 kDa |
| 翻译后修饰 | Ubiquitinated, leading to degradation by the proteosome. [UniProt] |
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