anti-NPHS2 / Podocin antibody
CAT.NO. : ARG40166
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NPHS2 / Podocin |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NPHS2 / Podocin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human NPHS2. |
| 偶联标记 | Un-conjugated |
| 別名 | SRN1; Podocin; PDCN |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Human fetal kidney | ||||||
| 实际分子量 | ~ 50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NPHS2 |
| 全名 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| 背景介绍 | This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| 生物功能 | Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. [UniProt] |
| 细胞定位 | Isoform 1: Cell membrane; Peripheral membrane protein. Isoform 2: Endoplasmic reticulum. [UniProt] |
| 预测分子量 | 42 kDa |
| 翻译后修饰 | Isoform 2 is glycosylated. [UniProt] |
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