anti-NPTX2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes NPTX2
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NPTX2
  • 抗原物种: Human
  • 抗原: A 16 amino acid peptide within aa. 170-220 of Human NPTX2.
  • Brand:
CAT.NO. : ARG42234
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes NPTX2
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NPTX2
抗原物种Human
抗原A 16 amino acid peptide within aa. 170-220 of Human NPTX2.
偶联标记Un-conjugated
別名Neuronal pentraxin II; Neuronal pentraxin-2; NP-II; NARP; NP2
应用说明
应用建议
应用推荐稀释比
IHC-P5 - 20 µg/ml
WB0.5 - 4 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量43 ~ 47 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide.
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4885 Human NPTX2

GeneID: 53324 Mouse NPTX2

Swiss-port # O70340 Mouse Neuronal pentraxin-2

Swiss-port # P47972 Human Neuronal pentraxin-2

基因名称NPTX2
全名neuronal pentraxin II
背景介绍This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]
生物功能Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity). [UniProt]
细胞定位Secreted. [UniProt]
预测分子量47 kDa
检测图片 (6)
  • ARG42234 anti-NPTX2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse brain tissue. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 hour at RT. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG42234 anti-NPTX2 antibody at 5 µg/ml dilution, overnight at 4°C.

  • ARG42234 anti-NPTX2 antibody WB image

    Western blot: 15 µg of Mouse brain lysate stained with ARG42234 anti-NPTX2 antibody at 0.5 or 1 µg/ml dilution and incubated at RT for 1 hour, in 5% NFDM/TBST.

  • ARG42234 anti-NPTX2 antibody IHC-P image

    Immunohistochemistry: 4% Paraformaldehyde-fixed Mouse brain tissue stained with ARG42234 anti-NPTX2 antibody (red) at 20 µg/ml dilution. DAPI (blue) for nuclear staining.

  • ARG42234 anti-NPTX2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human brain tissue. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 hour at RT. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG42234 anti-NPTX2 antibody at 5 µg/ml dilution, overnight at 4°C.

  • ARG42234 anti-NPTX2 antibody IHC-P image

    Immunohistochemistry: 4% Paraformaldehyde-fixed Human brain tissue stained with ARG42234 anti-NPTX2 antibody at 20 µg/ml dilution.

  • ARG42234 anti-NPTX2 antibody WB image

    Western blot: 15 µg of 293, A431, A549, CaCo-2, Daudi, HeLa, HepG2, K562, MCF-7, Jurkat, SK-N-SH, THP-1, NIH/3T3 and YB2/0 cell lysates stained with ARG42234 anti-NPTX2 antibody at 2 µg/ml dilution and incubated at RT for 1 hour, in 5% NFDM/TBST.

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