anti-NQO2 antibody
CAT.NO. : ARG40906
US$ Please choose
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概述
产品描述 | Rabbit Polyclonal antibody recognizes NQO2 |
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反应物种 | Ms, Rat |
应用 | FACS, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | NQO2 |
抗原物种 | Human |
抗原 | Synthetic peptide derived from Human NQO2. |
偶联标记 | Un-conjugated |
別名 | NRH dehydrogenase [quinone] 2; NMOR2; DHQV; Quinone reductase 2; NRH:quinone oxidoreductase 2; QR2; Ribosyldihydronicotinamide dehydrogenase [quinone]; DIA6; EC 1.10.5.1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Mouse heart |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q6AY80 Rat Ribosyldihydronicotinamide dehydrogenase [quinone] Swiss-port # Q9JI75 Mouse Ribosyldihydronicotinamide dehydrogenase [quinone] |
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基因名称 | NQO2 |
全名 | NAD(P)H dehydrogenase, quinone 2 |
背景介绍 | This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
生物功能 | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. [UniProt] |
细胞定位 | Cytoplasm. [UniProt] |
预测分子量 | 26 kDa |
