anti-NR0B1 / DAX1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes NR0B1 / DAX1
  • 反应物种: Hu, Ms
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NR0B1 / DAX1
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human NR0B1 (NP_000466.2)
  • Brand:
CAT.NO. : ARG55286
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes NR0B1 / DAX1
反应物种Hu, Ms
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NR0B1 / DAX1
抗原物种Human
抗原Recombinant protein of Human NR0B1 (NP_000466.2)
偶联标记Un-conjugated
別名AHC; GTD; SRXY2; DAX1; AHCH; DSS; NROB1; Nuclear receptor subfamily 0 group B member 1; HHG; Nuclear receptor DAX-1; DAX-1; AHX; DSS-AHC critical region on the X chromosome protein 1
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Jurkat
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 11614 Mouse NR0B1

GeneID: 190 Human NR0B1

Swiss-port # P51843 Human Nuclear receptor subfamily 0 group B member 1

Swiss-port # Q61066 Mouse Nuclear receptor subfamily 0 group B member 1

基因名称NR0B1
全名nuclear receptor subfamily 0, group B, member 1
背景介绍This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008]
生物功能Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). [UniProt]
研究领域Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
预测分子量52 kDa
检测图片 (2)
  • ARG55286 anti-NR0B1 / DAX1 antibody ICC/IF image

    Immunofluorescence: U2OS cells stained with ARG55286 anti-NR0B1 / DAX1 antibody.

  • ARG55286 anti-NR0B1 / DAX1 antibody WB image

    Western blot: Jurkat cell lysate stained with ARG55286 anti-NR0B1 / DAX1 antibody.

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