anti-NR0B1 / DAX1 antibody
CAT.NO. : ARG55286
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概述
产品描述 | Rabbit Polyclonal antibody recognizes NR0B1 / DAX1 |
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反应物种 | Hu, Ms |
应用 | ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | NR0B1 / DAX1 |
抗原物种 | Human |
抗原 | Recombinant protein of Human NR0B1 (NP_000466.2) |
偶联标记 | Un-conjugated |
別名 | AHC; GTD; SRXY2; DAX1; AHCH; DSS; NROB1; Nuclear receptor subfamily 0 group B member 1; HHG; Nuclear receptor DAX-1; DAX-1; AHX; DSS-AHC critical region on the X chromosome protein 1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Jurkat |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P51843 Human Nuclear receptor subfamily 0 group B member 1 Swiss-port # Q61066 Mouse Nuclear receptor subfamily 0 group B member 1 |
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基因名称 | NR0B1 |
全名 | nuclear receptor subfamily 0, group B, member 1 |
背景介绍 | This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008] |
生物功能 | Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). [UniProt] |
研究领域 | Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody |
预测分子量 | 52 kDa |
