anti-NR5A2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG58759
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes NR5A2 |
|---|---|
| 反应物种 | Hu, Pig |
| 预测物种 | Ms, Rat, Cow, Dog |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NR5A2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide from the internal region of Human NR5A2 (NP_995582.1; NP_003813.1). (C-TDYDRSPFVTSPIS) |
| 偶联标记 | Un-conjugated |
| 別名 | NR5A2; Nuclear Receptor Subfamily 5 Group A Member 2; LRH-1; FTZ-F1beta; FTZ-F1; HB1F-2; HB1F; B1F2; LRH1; FTF; CYP7A Promoter-Binding Factor; B1F; CPF; B1-Binding Factor, Hepatocyte Transcription Factor Which Activates Enhancer II Of Hepatitis B Virus; Nuclear Receptor Subfamily 5, Group A, Member 2; Fetoprotein-Alpha 1 (AFP) Transcription Factor; Alpha-1-Fetoprotein Transcription Factor; Hepatocytic Transcription Factor HB1F-3; Hepatocytic Transcription Factor; Liver Receptor Homolog-1; Liver Receptor Homolog 1; B1-Binding Factor |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 55 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Ammonium sulphate precipitation followed by affinity purification with immunogen. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O00482 Human Nuclear receptor subfamily 5 group A member 2 |
|---|---|
| 基因名称 | NR5A2 |
| 全名 | nuclear receptor subfamily 5, group A, member 2 |
| 背景介绍 | The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development. |
| 生物功能 | Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. |
| 细胞定位 | Nucleus |
| 预测分子量 | 61 kDa |
| 翻译后修饰 | Isopeptide bond, Ubl conjugation |
检测图片 (2)
ARG58759 anti-NR5A2 antibody WB image
Western blot: 35 µg of HepG2 nuclear lysate (in RIPA buffer) stained with ARG58759 anti-NR5A2 antibody at 1 µg/ml dilution. Primary incubation was 1 hour. Detected by chemiluminescence.
ARG58759 anti-NR5A2 antibody WB image
Western blot: 35 µg of Pig ovary lysate (in RIPA buffer) stained with ARG58759 anti-NR5A2 antibody at 0.3 µg/ml dilution. Primary incubation was 1 hour. Detected by chemiluminescence.
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