anti-NrCAM antibody [S364-51]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [S364-51] recognizes NrCAM
  • 反应物种: Ms, Rat
  • 应用: WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: S364-51
  • 同位型: IgG2a
  • 靶点名称: NrCAM
  • 抗原物种: Mouse
  • Brand:
CAT.NO. : ARG23976
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Product Details
概述
产品描述Mouse Monoclonal antibody [S364-51] recognizes NrCAM
反应物种Ms, Rat
应用WB
宿主Mouse
克隆Monoclonal
克隆号S364-51
同位型IgG2a
靶点名称NrCAM
抗原物种Mouse
抗原Fusion protein corresponding to aa. 30-845 (extracellular domain) of Mouse NrCAM.
偶联标记Un-conjugated
別名Nr-CAM; Ng-CAM-related; hBravo; Neuronal surface protein Bravo; Neuronal cell adhesion molecule; NgCAM-related cell adhesion molecule
应用说明
应用建议
应用推荐稀释比
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量~ 145 kDa
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.1% Sodium azide and 50% Glycerol.
抗菌剂0.1% Sodium azide
稳定剂50% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 319504 Mouse NRCAM

Swiss-port # Q810U4 Mouse Neuronal cell adhesion molecule

基因名称NRCAM
全名neuronal cell adhesion molecule
背景介绍Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
生物功能Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier (By similarity). [UniProt]
细胞定位Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Secreted. Note=Detected at nodes of Ranvier. [UniProt]
预测分子量144 kDa
检测图片 (1)
  • ARG23976 anti-NrCAM antibody [S364-51] WB image

    Western blot: 10 µg of Rat brain membrane lysate stained with ARG23976 anti-NrCAM antibody [S364-51] at 1:1000 dilution, for 1 hour at RT.

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