anti-NUDT5 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal recognizes NUDT5
  • 反应物种: Hu, Rat
  • 应用: FACS, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NUDT5
  • 抗原物种: Human
  • 抗原: Human NUDT5 recombinant protein (Position: M1-F219).
  • Brand:
CAT.NO. : ARG44130
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Product Details
概述
产品描述Rabbit Polyclonal recognizes NUDT5
反应物种Hu, Rat
应用FACS, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NUDT5
抗原物种Human
抗原Human NUDT5 recombinant protein (Position: M1-F219).
偶联标记Un-conjugated
別名NUDT5; Nudix Hydrolase 5; YSA1H; Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5; Nuclear ATP-Synthesis Protein NUDIX5; ADP-Sugar Pyrophosphatase; 8-Oxo-DGDP Phosphatase; HYSAH1; HNUDT5; Nucleoside Diphosphate-Linked Moiety X Motif 5; Nudix Motif 5; EC 3.6.1.13; EC 3.6.1.58; EC 2.7.7.96; NUDIX5; YSAH1; YSA1
应用说明
应用建议
应用推荐稀释比
FACS1 - 3 µg/10^6 cells
IHC-P2 - 5 µg/ml
WB0.25 - 0.5 µg/ml
应用说明The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂0.05% Sodium azide
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 11164 Human NUDT5

GeneID: 361274 Rat NUDT5

Swiss-port # Q6AY63 Rat ADP-sugar pyrophosphatase

Swiss-port # Q9UKK9 Human ADP-sugar pyrophosphatase

基因名称NUDT5
全名Nudix Hydrolase 5
背景介绍This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.
生物功能Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate.
细胞定位Nucleus
预测分子量24 kDa
翻译后修饰Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation
检测图片 (4)
  • ARG44130 anti-NUDT5 antibody IHC-P image

    Immunohistochemistry: Human lung stained with ARG44130 anti-NUDT5 antibody at 2 μg/ml dilution.

  • ARG44130 anti-NUDT5 antibody WB image

    Western blot: HeLa, 293T, HepG2 and Jurkat stained with ARG44130 anti-NUDT5 antibody at 0.5 μg/ml dilution.

  • ARG44130 anti-NUDT5 antibody FACS image

    Flow Cytometry: 293T stained with ARG44130 anti-NUDT5 antibody at 1 µg/10^6 cells dilution.

  • ARG44130 anti-NUDT5 antibody WB image

    Western blot: RH35 stained with ARG44130 anti-NUDT5 antibody at 0.5 μg/ml dilution.

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