anti-OB Cadherin antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes OB Cadherin
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: OB Cadherin
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 637-796 of Human OB Cadherin (NP_001788.2).
  • Brand:
CAT.NO. : ARG40238
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes OB Cadherin
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称OB Cadherin
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 637-796 of Human OB Cadherin (NP_001788.2).
偶联标记Un-conjugated
別名CDHOB; OB-cadherin; Osteoblast cadherin; Cadherin-11; OB; OSF-4; CAD11
应用说明
预测反应性说明Rat
应用建议
应用推荐稀释比
WB1:500 - 1:3000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse spleen and SKOV3
实际分子量110 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1009 Human CDH11

GeneID: 12552 Mouse CDH11

Swiss-port # P55287 Human Cadherin-11

Swiss-port # P55288 Mouse Cadherin-11

基因名称CDH11
全名cadherin 11, type 2, OB-cadherin (osteoblast)
背景介绍This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
生物功能Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. [UniProt]
细胞定位Cell membrane, Single-pass type I membrane protein. [UniProt]
预测分子量88 kDa
检测图片 (3)
  • ARG40238 anti-OB Cadherin antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG40238 anti-OB Cadherin antibody at 1:100 dilution.

  • ARG40238 anti-OB Cadherin antibody WB image

    Western blot: 25 µg of SKOV3 cell lysate stained with ARG40238 anti-OB Cadherin antibody at 1:3000 dilution.

  • ARG40238 anti-OB Cadherin antibody WB image

    Western blot: 25 µg of Mouse spleen lysate stained with ARG40238 anti-OB Cadherin antibody at 1:3000 dilution.

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