anti-ORAI1 / CRACM1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes ORAI1 / CRACM1
  • 反应物种: Hu
  • 预测物种: Dog, Pig
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ORAI1 / CRACM1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG64804
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes ORAI1 / CRACM1
反应物种Hu
预测物种Dog, Pig
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称ORAI1 / CRACM1
抗原物种Human
抗原C-KKQPGQPRPTSKP
偶联标记Un-conjugated
別名Protein orai-1; CRACM1; Transmembrane protein 142A; IMD9; ORAT1; Calcium release-activated calcium channel protein 1; TAM2; TMEM142A
应用说明
应用建议
应用推荐稀释比
WB0.03 - 0.1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 84876 Human ORAI1

Swiss-port # Q96D31 Human Calcium release-activated calcium channel protein 1

背景介绍The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]
研究领域Immune System antibody; Signaling Transduction antibody
预测分子量33 kDa
翻译后修饰N-glycosylated.
Ubiquitinated.
Cys-195 is oxidated, leading to inactivate channel activity.
检测图片 (2)
  • ARG64804 anti-ORAI1 / CRACM1 antibody WB image

    Western Blot: Human Placenta lysate (35 µg protein in RIPA buffer) stained with ARG64804 anti-ORAI1 / CRACM1 antibody at 0.03 µg/ml dilution.

  • ARG64804 anti-ORAI1 / CRACM1 antibody WB image

    Western blot: 35 µg of Human skin lysate (in RIPA buffer) stained with ARG64804 anti-ORAI1 / CRACM1 antibody at 0.1 µg/ml dilution and incubated at RT for 1 hour.

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