anti-ORAI1 / CRACM1 antibody
CAT.NO. : ARG64804
US$ Please choose
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概述
产品描述 | Goat Polyclonal antibody recognizes ORAI1 / CRACM1 |
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反应物种 | Hu |
预测物种 | Dog, Pig |
应用 | WB |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ORAI1 / CRACM1 |
抗原物种 | Human |
抗原 | C-KKQPGQPRPTSKP |
偶联标记 | Un-conjugated |
別名 | Protein orai-1; CRACM1; Transmembrane protein 142A; IMD9; ORAT1; Calcium release-activated calcium channel protein 1; TAM2; TMEM142A |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q96D31 Human Calcium release-activated calcium channel protein 1 |
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背景介绍 | The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011] |
研究领域 | Immune System antibody; Signaling Transduction antibody |
预测分子量 | 33 kDa |
翻译后修饰 | N-glycosylated. Ubiquitinated. Cys-195 is oxidated, leading to inactivate channel activity. |
检测图片 (2)
ARG64804 anti-ORAI1 / CRACM1 antibody WB image
Western Blot: Human Placenta lysate (35 µg protein in RIPA buffer) stained with ARG64804 anti-ORAI1 / CRACM1 antibody at 0.03 µg/ml dilution.
ARG64804 anti-ORAI1 / CRACM1 antibody WB image
Western blot: 35 µg of Human skin lysate (in RIPA buffer) stained with ARG64804 anti-ORAI1 / CRACM1 antibody at 0.1 µg/ml dilution and incubated at RT for 1 hour.
