anti-Ornithine Decarboxylase antibody
CAT.NO. : ARG40522
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概述
产品描述 | Rabbit Polyclonal antibody recognizes Ornithine Decarboxylase |
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反应物种 | Hu, Ms, Rat |
应用 | ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | Ornithine Decarboxylase |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 1-280 of Human Ornithine Decarboxylase (NP_002530.1). |
偶联标记 | Un-conjugated |
別名 | Ornithine decarboxylase; ODC; EC 4.1.1.17 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | HeLa | ||||||
实际分子量 | 50 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | ODC1 |
全名 | ornithine decarboxylase 1 |
背景介绍 | This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013] |
生物功能 | Key enzyme of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. [UniProt] |
预测分子量 | 51 kDa |
翻译后修饰 | S-Nitrosylation inhibits the enzyme. S-Nitrosylated in vitro on 4 cysteine residues. [UniProt] |
