anti-OTC / Ornithine Carbamoyltransferase antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG58999
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes OTC / Ornithine Carbamoyltransferase |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | OTC / Ornithine Carbamoyltransferase |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 71-98 of Human OTC / Ornithine Carbamoyltransferase. |
| 偶联标记 | Un-conjugated |
| 別名 | Ornithine transcarbamylase; OCTD; EC 2.1.3.3; Ornithine carbamoyltransferase, mitochondrial; OTCase |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Human liver |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P00480 Human Ornithine carbamoyltransferase, mitochondrial |
|---|---|
| 基因名称 | OTC |
| 全名 | ornithine carbamoyltransferase |
| 背景介绍 | This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq, Jul 2008] |
| 细胞定位 | Mitochondrion matrix. [UniProt] |
| 预测分子量 | 40 kDa |
| 翻译后修饰 | Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. [UniProt] |
检测图片 (2)
ARG58999 anti-OTC / Ornithine Carbamoyltransferase antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human hepatoarcinoma stained with ARG58999 anti-OTC / Ornithine Carbamoyltransferase antibody.
ARG58999 anti-OTC / Ornithine Carbamoyltransferase antibody WB image
Western blot: 20 µg of Human liver lysate stained with ARG58999 anti-OTC / Ornithine Carbamoyltransferase antibody at 1:1000 dilution.
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