anti-p19 INK4d antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG54677
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes p19 INK4d |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | p19 INK4d |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide within 15-43 aa (N-terminus) of Human p19 INK4d protein (NP_001791.1). |
| 偶联标记 | Un-conjugated |
| 別名 | p19-INK4D; p19; Cyclin-dependent kinase 4 inhibitor D; p19-INK4d; INK4D |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Mouse testis |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P55273 Human Cyclin-dependent kinase 4 inhibitor D Swiss-port # Q60773 Mouse Cyclin-dependent kinase 4 inhibitor D |
|---|---|
| 基因名称 | CDKN2D |
| 全名 | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| 背景介绍 | P19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008] |
| 细胞定位 | Nucleus, Cytoplasm |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody |
| 预测分子量 | 18 kDa |
检测图片 (3)
ARG54677 anti-p19 INK4d antibody IHC image
Immunohistochemistry: Formalin fixed and paraffin embedded testis tissue stained with ARG54677 anti-p19 INK4d antibody.
ARG54677 anti-p19 INK4d antibody WB image
Western blot: 35 µg of Mouse testis lysate stained with ARG54677 anti-p19 INK4d antibody.
ARG54677 anti-p19 INK4d antibody FACS image
Flow Cytometry: HeLa cells stained with ARG54677 anti-p19 INK4d antibody (right histogram) or without primary antibody control (left histogram).
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