anti-p19 INK4d antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes p19 INK4d
  • 反应物种: Hu, Ms
  • 应用: FACS, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: p19 INK4d
  • 抗原物种: Human
  • 抗原: KLH-conjugated synthetic peptide within 15-43 aa (N-terminus) of Human p19 INK4d protein (NP_001791.1).
  • Brand:
CAT.NO. : ARG54677
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes p19 INK4d
反应物种Hu, Ms
应用FACS, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称p19 INK4d
抗原物种Human
抗原KLH-conjugated synthetic peptide within 15-43 aa (N-terminus) of Human p19 INK4d protein (NP_001791.1).
偶联标记Un-conjugated
別名p19-INK4D; p19; Cyclin-dependent kinase 4 inhibitor D; p19-INK4d; INK4D
应用说明
应用建议
应用推荐稀释比
FACS1:10 - 1:50
IHC-PAssay-dependent
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse testis
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS and 0.09% (W/V) Sodium azide
抗菌剂0.09% (W/V) Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1032 Human CDKN2D

GeneID: 12581 Mouse CDKN2D

Swiss-port # P55273 Human Cyclin-dependent kinase 4 inhibitor D

Swiss-port # Q60773 Mouse Cyclin-dependent kinase 4 inhibitor D

基因名称CDKN2D
全名cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
背景介绍P19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
细胞定位Nucleus, Cytoplasm
研究领域Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody
预测分子量18 kDa
检测图片 (3)
  • ARG54677 anti-p19 INK4d antibody IHC image

    Immunohistochemistry: Formalin fixed and paraffin embedded testis tissue stained with ARG54677 anti-p19 INK4d antibody.

  • ARG54677 anti-p19 INK4d antibody WB image

    Western blot: 35 µg of Mouse testis lysate stained with ARG54677 anti-p19 INK4d antibody.

  • ARG54677 anti-p19 INK4d antibody FACS image

    Flow Cytometry: HeLa cells stained with ARG54677 anti-p19 INK4d antibody (right histogram) or without primary antibody control (left histogram).

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