anti-PAAF1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44447
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PAAF1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PAAF1 |
| 抗原物种 | Human |
| 抗原 | Human PAAF1 recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | PAAF1; Proteasomal ATPase Associated Factor 1; Rpn14; WDR71; Proteasomal ATPase-Associated Factor 1; WD Repeat-Containing Protein 71; WD Repeat Domain 71; FLJ11848; Protein G-16; PAAF |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | Swiss-port # Q9BRP4 Human Proteasomal ATPase-associated factor 1 |
|---|---|
| 基因名称 | PAAF1 |
| 全名 | Proteasomal ATPase Associated Factor 1 |
| 背景介绍 | This gene encodes a WD repeat-containing protein involved in regulation of association of proteasome components. During HIV infection, the encoded protein is thought to promote provirus transcription through recruitment of the 19S regulatory complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| 生物功能 | Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation. |
| 细胞定位 | Proteasome |
| 预测分子量 | 42 kDa |
| 翻译后修饰 | Acetylation |
检测图片 (3)
ARG44447 anti-PAAF1 antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG44447 anti-PAAF1 antibody at 5 μg/mL dilution.
ARG44447 anti-PAAF1 antibody WB image
Western blot: 293T and U251 stained with ARG44447 anti-PAAF1 antibody at 0.5 μg/mL dilution.
ARG44447 anti-PAAF1 antibody FACS image
Flow Cytometry: JK stained with ARG44447 anti-PAAF1 antibody at 1 μg/10^6 cells dilution.
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