anti-PAICS / PAIS antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PAICS / PAIS
  • 反应物种: Hu, Rat
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PAICS / PAIS
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human PAICS
  • Brand:
CAT.NO. : ARG44372
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PAICS / PAIS
反应物种Hu, Rat
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PAICS / PAIS
抗原物种Human
抗原Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human PAICS
偶联标记Un-conjugated
別名PAICS; Phosphoribosylaminoimidazole Carboxylase And Phosphoribosylaminoimidazolesuccinocarboxamide Synthase; AIRC; ADE2H1; PAIS; Bifunctional Phosphoribosylaminoimidazole Carboxylase/Phosphoribosylaminoimidazole Succinocarboxamide Synthetase; Phosphoribosylaminoimidazole Carboxylase, Phosphoribosylaminoimidazole Succinocarboxamide Synthetase; ADE2; Phosphoribosylaminoimidazole Carboxylase; Phosphoribosylaminoimidazolesuccinocarboxamide Synthase; Multifunctional Protein ADE2H1; Multifunctional Protein ADE2; SAICAR Synthetase; AIR Carboxylase; PAICSD
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% sodium azide and 50% Glycerol.
抗菌剂0.02% sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10606 Human PAICS

GeneID: 140946 Rat PAICS

Swiss-port # P22234 Human Multifunctional protein ADE2

Swiss-port # P51583 Rat Multifunctional protein ADE2

基因名称PAICS
全名Phosphoribosylaminoimidazole Carboxylase And Phosphoribosylaminoimidazolesuccinocarboxamide Synthase
背景介绍This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
生物功能Bifunctional phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase catalyzing two reactions of the de novo purine biosynthetic pathway.
研究领域Disease variant
预测分子量47 kDa
翻译后修饰Acetylation, Phosphoprotein
检测图片 (2)
  • ARG44372 anti-PAICS / PAIS antibody ICC/IF image

    Immunofluorescence: U2OS stained with ARG44372 anti-PAICS / PAIS antibody at 1:50 dilution.

  • ARG44372 anti-PAICS / PAIS antibody WB image

    Western blot: Jurkat, 293T, SW620, Raji and HeLa stained with ARG44372 anti-PAICS / PAIS antibody at 1:1000 dilution.

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