anti-PAIP2 antibody [1C12]

CAT.NO. : ARG57008

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [1C12] recognizes PAIP2
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	1C12
同位型	IgG2b
靶点名称	PAIP2
抗原物种	Human
抗原	Recombinant fragment around aa. 1-127 of Human PAIP2.
偶联标记	Un-conjugated
別名	A; PABP-interacting protein 2; Poly; PAIP-2; Polyadenylate-binding protein-interacting protein 2; PAIP2A

应用说明

应用建议

应用	推荐稀释比
WB	1:500 - 1:5000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 51247 Human PAIP2 Swiss-port # Q9BPZ3 Human Polyadenylate-binding protein-interacting protein 2
基因名称	PAIP2
全名	poly(A) binding protein interacting protein 2
生物功能	Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. [UniProt]
预测分子量	15 kDa
翻译后修饰	Ubiquitinated, leading to its degradation by the proteasome.

检测图片 (1)

ARG57008 anti-PAIP2 antibody [1C12] WB image
Western blot: 40 µg of HeLa cell lysate stained with ARG57008 anti-PAIP2 antibody [1C12] at 1:1000.

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