anti-PAPSS2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44067
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Product Details
概述
| 产品描述 | Rabbit Polyclonal recognizes PAPSS2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PAPSS2 |
| 抗原物种 | Human |
| 抗原 | Human PAPSS2 recombinant protein (Position: E212-H320). |
| 偶联标记 | Un-conjugated |
| 別名 | PAPSS2; 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2; ATPSK2; Bifunctional 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2; PAPS Synthase 2; Adenosine 5'-Phosphosulfate Kinase; SK 2; SK2; Bifunctional 3'-Phosphoadenosine 5'-Phosphosulfate Synthethase 2; 3-Prime-Phosphoadenosine 5-Prime-Phosphosulfate Synthase 2; ATP Sulfurylase/Adenosine 5'-Phosphosulfate Kinase; Epididymis Secretory Sperm Binding Protein; ATP Sulfurylase/APS Kinase 2; Sulfate Adenylyltransferase; Adenylyl-Sulfate Kinase; Sulfurylase Kinase 2; PAPS Synthetase 2; EC 2.7.1.25; PAPSS 2; BCYM4 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O88428 Mouse Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Swiss-port # O95340 Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
|---|---|
| 基因名称 | PAPSS2 |
| 全名 | 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2 |
| 背景介绍 | Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. |
| 生物功能 | Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases. |
| 细胞定位 | Cytosol |
| 预测分子量 | 70 kDa |
检测图片 (3)
ARG44067 anti-PAPSS2 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44067 anti-PAPSS2 antibody at 1 μg/1x10^6 cells dilution.
ARG44067 anti-PAPSS2 antibody WB image
Western blot: rat liver and rat kidney stained with ARG44067 anti-PAPSS2 antibody at 0.5 μg/mL dilution.
ARG44067 anti-PAPSS2 antibody WB image
Western blot: mouse liver and mouse kidney stained with ARG44067 anti-PAPSS2 antibody at 0.5 μg/mL dilution.
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