anti-PARP2 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes PARP2
  • 反应物种: Hu
  • 应用: IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PARP2
  • 抗原物种: Human
  • 抗原: C-LDLFEVEKDGEKE
  • Brand:
CAT.NO. : ARG63904
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes PARP2
反应物种Hu
应用IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称PARP2
抗原物种Human
抗原C-LDLFEVEKDGEKE
偶联标记Un-conjugated
別名EC 2.4.2.30; hPARP-2; ARTD2; NAD; pADPRT-2; PARP-2; Poly [ADP-ribose] polymerase 2; Poly[ADP-ribose] synthase 2; ADP-ribosyltransferase diphtheria toxin-like 2; ADPRT-2; ADPRTL2; ADPRTL3; ADPRT2
应用说明
应用建议
应用推荐稀释比
IHC-P5 µg/ml
WB1 - 3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10038 Human PARP2

Swiss-port # Q9UGN5 Human Poly [ADP-ribose] polymerase 2

背景介绍This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]
研究领域Gene Regulation antibody
预测分子量66 kDa
翻译后修饰Poly-ADP-ribosylated by PARP1.
Acetylation reduces DNA binding and enzymatic activity.
检测图片 (3)
  • ARG63904 anti-PARP2 antibody WB image

    Western Blot: Human Spleen Lysate (35 µg protein in RIPA buffer) stained with ARG63904 anti-PARP2 antibody at 1 µg/ml dilution.

  • ARG63904 anti-PARP2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human skin tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63904 anti-PARP2 antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG63904 anti-PARP2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human adrenal gland tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63904 anti-PARP2 antibody at 5 µg/ml dilution followed by AP-staining.

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