anti-PCCA antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PCCA
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PCCA
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein containing a sequence corresponding to amino acids 449-728 of human PCCA
  • Brand:
CAT.NO. : ARG44379
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PCCA
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PCCA
抗原物种Human
抗原Recombinant fusion protein containing a sequence corresponding to amino acids 449-728 of human PCCA
偶联标记Un-conjugated
別名PCCA; Propionyl-CoA Carboxylase Subunit Alpha; Propionyl-CoA Carboxylase Alpha Chain, Mitochondrial; Propionyl Coenzyme A Carboxylase, Alpha Polypeptide; EC 6.4.1.3; Propanoyl-CoA:Carbon Dioxide Ligase Alpha Subunit; Propanoyl-CoA:Carbon Dioxide Ligase Subunit Alpha; Propionyl CoA Carboxylase, Alpha Polypeptide; Propionyl-CoA Carboxylase Alpha Subunit; PccA Complementation Group; PCCase Alpha Subunit; PCCase Subunit Alpha
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
WB1:1000 - 1:3000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.01% Thimerosal and 50% Glycerol.
抗菌剂0.01% Thimerosal
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 110821 Mouse PCCA

GeneID: 5095 Human PCCA

GeneID: 687008 Rat PCCA

基因名称PCCA
全名Propionyl-CoA Carboxylase Subunit Alpha
背景介绍The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.
生物功能This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites
细胞定位Mitochondrion
预测分子量80 kDa
翻译后修饰Acetylation,Phosphoprotein
检测图片 (5)
  • ARG44379 anti-PCCA antibody IHC-P image

    Immunohistochemistry: Human liver stained with ARG44379 anti-PCCA antibody at 1:100 dilution.

  • ARG44379 anti-PCCA antibody IHC-P image

    Immunohistochemistry: Rat brain stained with ARG44379 anti-PCCA antibody at 1:100 dilution.

  • ARG44379 anti-PCCA antibody WB image

    Western blot: Rat kidney stained with ARG44379 anti-PCCA antibody at 1:3000 dilution.

  • ARG44379 anti-PCCA antibody IHC-P image

    Immunohistochemistry: Mouse kidney stained with ARG44379 anti-PCCA antibody at 1:100 dilution.

  • ARG44379 anti-PCCA antibody WB image

    Western blot: Mouse liver, Mouse brain and Mouse kidney stained with ARG44379 anti-PCCA antibody at 1:3000 dilution.

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