anti-PDE1A antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG10791
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PDE1A |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | Confocal, Dot, ELISA, ICC/IF, IHC, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PDE1A |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide around aa. 1-50 from Mouse PDE1A protein. Common to all PDE1A variants. |
| 偶联标记 | Un-conjugated |
| 別名 | CAM-PDE-1A; Cam-PDE 1A; HCAM1; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; EC 3.1.4.17; HSPDE1A; hCam-1; HCAM-1; 61 kDa Cam-PDE |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 30% Glycerol and 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P54750 Human Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Swiss-port # Q61481 Mouse Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A |
|---|---|
| 基因名称 | Pde1a |
| 全名 | phosphodiesterase 1A, calmodulin-dependent |
| 背景介绍 | Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009] |
| 生物功能 | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP. [UniProt] |
| 预测分子量 | 61 kDa |
检测图片 (1)
ARG10791 anti-PDE1A antibody WB image
Western blot: Recombinant PDE1A protein stained with ARG10791 anti-PDE1A antibody at 1:500 dilution.
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